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                                                                                       Acting address for Enzymatica AB (publ)JANUARY-SEPTEMBER 2018                                                                                                                                                                     Breakthrough acceding for Japan and lower sales in Q3 due to restrictions in Germany

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Q3          

Significant contest in Q3

First nine months                                                                                                                                                         

Significant contest afterwards the quarter

         CEO statement: Able abstracts from German multicenter study

The best important accident for Enzymatica back the aftermost acting address was the address on the basic after-effects from the multicenter abstraction in Germany, which we presented on October 1. In this explorative abstraction we advised the adeptness of four altered algid scales to ascertain the absolute furnishings of ColdZyme compared with a accumulation that was not advised with our product. Although the after-effects are preliminary, I can achieve that these abstracts assuming the absolute furnishings of ColdZyme are acutely strong. All four evidence scales were able to appearance a cogent bigger aftereffect back application ColdZyme than after treatment. In addition, the use of medicines for appropriate abatement of colds was decidedly lower amid those who acclimated ColdZyme. The consistently absolute after-effects strongly indicates that ColdZyme reduces both the acuteness of affection and the continuance of colds.

Third-quarter sales were lower than the agnate division aftermost year. This abatement is mainly due to two factors: the balmy summer and the cardinal in Germany apropos business of ViruProtect, which is the cast beneath which ColdZyme is awash in Germany. The balmy summer throughout Europe resulted in beneath colds and a accepted abatement in sales of algid products, which additionally afflicted our sales, admitting to a bottom admeasurement than in the bazaar as a whole.

As a aftereffect of the cloister cardinal in Germany, which we accept appear earlier, restrictions accept been imposed on our accomplice apropos the business of ViruProtect. Although German pharmacies may abide to advertise the absolute artefact stock, inventories may not be restocked as connected as the cardinal is in effect. Consequently, our German accomplice will not be able to abode any new orders for the German bazaar until added notice. The cardinal applies alone to Germany, but not to ViruProtect sales in Austria and Belgium. The accomplishments is that German legislation on artefact claims of medical accessory articles is stricter than in the blow of the EU. Our accomplice has appealed the cardinal and we are additionally alive on deepening the affidavit for ColdZyme in adjustment to be able to resume sales of the artefact in Germany.

We are admiring to address that ColdZyme continues to abduction bazaar allotment in Sweden. During the third quarter, the absolute algid antidote bazaar beneath by 2.4% in volume, while sales of ColdZyme rose by 7%. On a rolling 12-month base our bazaar allotment (7 and 20 ml combined) added from 4.9% to 5.3% compared with the aforementioned aeon the antecedent year. Moreover, ColdZyme thereby anesthetized Nezeril and is now the fifth bigger algid cast in Sweden.

Strong efforts are underway to assurance benefactor agreements for new markets. During the division we active a arrangement with ABEX Pharmaceuticals for sales and business of ColdZyme for the South African market. This absolute biologic aggregation has able administration channels and the barrage of ColdZyme is planned for the 2019 winter season. With sales in the southern hemisphere, area the algid division extends from March through August, we will see some leveling of the accepted melancholia aberration in sales.

After the aing of the advertisement aeon we active a arrangement with one of the bigger Japanese biologic companies apropos registration, marketing, administration and sales of ColdZyme. The arrangement is a anniversary in Enzymatica’s development and provides us with admission to one of the world’s bigger bloom affliction markets with a citizenry of about 127 million, as able-bodied as a algid antidote bazaar with anniversary sales of about SEK 10 billion. This is the added absolutely ample partner, in accession to STADA, with which we accept active a arrangement and we accept appropriately already afresh accustomed acceptance of our barrier technology.

To ensure our abiding costs the Board of Directors proposed in October that Enzymatica should float a rights affair of about SEK 98.7 million. The bang of basic will primarily be acclimated to advance our ytic ysis affairs and for our connected all-embracing expansion, as able-bodied as claim of a arch accommodation from June. The Board of Directors intends to defended the rights affair to 100 percent through cable commitments and underwriting agreements.

With the after-effects from the German multicenter abstraction and the acceding for the Japanese bazaar I accept an alike stronger absolute appearance of Enzymatica’s future. We are now continuing our efforts in a aerial clip for added studies to scientifically abutment ColdZyme’s absolute furnishings and to assurance benefactor agreements for added markets.

Fredrik Lindberg, CEO

For questions about this report, amuse contact:Fredrik Lindberg, CEO, Enzymatica AB Tel: 46 (0)708-86 53 70 | Email: [email protected]

Therese Filmersson, CFO, Enzymatica AB Tel: 46 (0)708-40 72 24 | Email: [email protected]

PublicationThis advice is advice that Enzymatica is obliged to accomplish accessible pursuant to the EU Bazaar Abuse Regulation. The advice was submitted for publication, through the bureau of the acquaintance being set out above, at 8:30 a.m. CET on October 31, 2018.

Street addressEnzymatica AB (publ) Corporate character no.: 556719-9244 Mailing address: Ideon Science Park, 223 70 LUND Street address: Scheelevägen 19, Ideon, Lund Tel: 46 (0)46-286 31 00 | [email protected] | www.enzymatica.se

Enzymatica is listed on the Nasdaq First North. The Aggregation is traded beneath the ticker attribute ENZY and ISIN cipher SE0003943620. Enzymatica’s certified adviser is Erik Penser Bank.

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